Data from a Phase I trial of Avmapki Fakzynja also supports the regimen's tolerability and suggests its potential activity in ...

Model includes age, body mass index, hypertriglyceridemia, tumor staging, tumor grade, CA125 level, platelet count, fibrinogen level.

A pairing of two experimental drugs inhibits tumor growth and blocks drug-induced resistance in ovarian cancer, according to ...

These findings form the basis for the GRACED study, a study protocol in which granulosa cell tumor patients receive treatment based on the laboratory response of their own tumor cells. This represents ...

A research team has uncovered a novel molecular pathway linking oxidative stress to cell death in pig ovarian follicles, ...

A newly identified long noncoding RNA (lncRNA), named lnc2300, plays a protective role in ovarian granulosa cells but is ...

Forkhead box protein L2 (FOXL2) is a protein involved in ovary development and maintenance, among other functions. Mutations in its gene are involved in ovarian failure and granulosa cell tumors, ...

Epithelial ovarian cancer is the most common type of ovarian cancer. Rare types of ovarian cancer include germ cell tumours (teratomas and dysgerminomas), stromal tumours (granulosa tumours) and ...

juvenile granulosa cell tumours are rarer and usually develop before puberty Granulosa cell tumours often produce hormones and are called functioning tumours. They make the female hormone oestrogen.

Mature egg cells, or oocytes, are essential for fertilization in assisted reproductive technologies. However, some 'denuded' oocytes, or those lacking the protective granulosa cell layer, fail to ...

Juvenile granulosa-cell tumors account for only 2 to 5% of all ovarian tumors, but they are the most common malignant sex cord–stromal tumors of the ovary in adolescents, occurring at a mean age ...