Ovarian granulosa cell tumors (OGCT) are the most frequent kind of sex cord-stromal tumors, and represent ∼2–5% of all ovarian malignancies. OGCTs exist as two entities, juvenile and adult ...

Our granulosa-like cells have transcriptomes similar to human fetal ovarian cells and recapitulate key ovarian phenotypes including follicle formation and steroidogenesis.

A 23-year-old woman presented with a 7 cm right multicystic mass in the ovary, which corresponded microscopically to an unusual lesion consisting of a multifocal granulosa cell tumor with ...

A research team has uncovered a novel molecular pathway linking oxidative stress to cell death in pig ovarian follicles, ...

juvenile granulosa cell tumour and your cancer is stage 1C or greater; adult granulosa cell tumour and your cancer is stage 1C2 or greater; a sertoli–leydig cell tumour and the cells look very ...

Primordial germ cells (PGCs) migrate to the developing gonads and proliferate. Gonadal somatic cells differentiate into ovarian stroma, granulosa, and theca cells.

Juvenile granulosa-cell tumors account for only 2 to 5% of all ovarian tumors, but they are the most common malignant sex cord–stromal tumors of the ovary in adolescents, occurring at a mean age ...

While most ovarian research focuses on the development of oocytes and surrounding granulosa cells, little is known about the cellular composition of ovarian stroma cells.

Germ cell ovarian tumours begin in the ovarian cells that develop into eggs. ... Granulosa cell tumours are the most common type. Borderline ovarian tumours. Borderline ovarian tumours are abnormal ...

The new study used cells from mouse ovaries – called granulosa cells – to create induced pluripotent stem cells (iPSCs), which can differentiate into any cell type. In the lab, the granulosa-derived ...

These findings form the basis for the GRACED study, a study protocol in which granulosa cell tumor patients receive treatment based on the laboratory response of their own tumor cells. This represents ...

Revitalising an aged egg cell. An ovarian follicle is a basic functional unit in the mammalian ovary, composed of somatic cells (granulosa cells) that surround and support an oocyte (an immature ...