The study uncovers how ovarian ECM tropism influences endometriotic cell adhesion, paving the way for novel strategies to ...

Obstructive nephropathy is one of the leading causes of kidney injury and fibrosis, which can lead to end-stage renal disease (ESRD). Stromal vascular fraction (SVF), a heterogeneous cell mixture ...

We found that SLIT3, produced by cardiac stromal cells, that is, cardiac fibroblasts and vascular mural cells, can stimulate hypertrophy and fibrosis induced by pressure overload. We also found that ...

Synopsis Loss of Cep120 in renal stromal progenitors disrupts centrosome biogenesis, growth and fate of interstitial cells, resulting in hypoplastic kidneys. Defective centrosome formation also ...

A cystic fibrosis drug called Trikafta is widely available in the U.S. and Europe. It has transformed life for tens of thousands of people with the disease in high-income countries. But what ...

Background: Conversion of cardiac stromal cells into myofibroblasts is typically associated with hypoxia conditions, metabolic insults, and/or inflammation, all of which are predisposing factors to ...

Mesenchymal stromal cells (MSCs) lessened lung scarring by reducing idiopathic pulmonary fibrosis (IPF)-related aging of lung cells that play a key role in tissue repair, according to a study in a ...

Keywords: Meflin, Islr, cancer-associated fibroblast, mesenchymal stromal/stem cell, tumour microenvironment, fibrosis Citation: Takahashi M, Kobayashi H, Mizutani Y, Hara A, Iida T, Miyai Y, Asai N ...

Mesenchymal stromal cells, or MSCs, are multipotent and self-renewing, much like stem cells, and they have been studied for their potential to treat conditions like fibrosis.