Traffic is severely backed up in the southbound lanes of I-81 in Franklin County due to a crash in Washington County, Md.

A disabled tractor-trailer caused severe delays on Interstate 81 in Dauphin County, according to PennDOT. Video above: ...

A Hagerstown, Md., man faces charges after a woman's 911 call claiming kidnapping led to police tracking down a Toyota Rav 4 ...

A tractor-trailer accident on Interstate 81 on Monday prompted hazmat teams to clear the scene before anyone could drive through the area again safely.

Four teens on a crime spree were headed to Connecticut but drew the attention of PSP after pointing a gun at another motorist ...

State Police say Manuel De Jesus Ascencio Castro, 32, led police on a high-speed chase on the highway with a woman and three ...

The New York State Department of Transportation (NYSDOT) is letting drivers know of lane closures on Interstate 81 southbound ...

Police closed the Main Avenue exit and on-ramps for I-81 South after a pedestrian was struck Wednesday morning.

TROOPERS SAY THEY WERE CALLED TO THE CARLISLE, MECHANICSBURG AREA OF INTERSTATE 81 FOR A PASSENGER IN A RED TOYOTA TUNDRA PICKUP TRUCK POINTING A GUN AT OTHER DRIVERS. AROUND 1230 YESTERDAY AFTERNOON.

Cortland County, N.Y. — Interstate 81 north bound is closed to all traffic at Exit 54 (Cortland/Homer) after multiple crashes ...

GREENVILLE — Portions of Interstate 81 were closed Monday for several hours in Augusta County following the crash of a tanker-truck that was carrying ammonia, authorities said. VDOT reported all ...