The San Francisco 49ers (6-10) are 4.5-point underdogs as they try to break their three-game losing streak in a matchup ...

The San Francisco 49ers missed the playoffs entirely after making it to the Super Bowl last season. They will have some big ...

While the San Francisco 49ers chances of a spot in the playoffs have been decided for some time now, their loss in Week 18 to ...

What channel is 49ers vs Cardinals game on today? How to watch San Francisco vs Arizona NFL Week 18 football game on TV, ...

DFS millionaire Mike McClure shares his top daily Fantasy football picks for San Francisco 49ers vs. Detroit lions on MNF ...

Micah Roberts has revealed his NFL Monday Night Football bets and NFL picks against the spread for Detroit vs. San Francisco ...

In a display of nepo baby solidarity, San Francisco 49ers head coach Kyle Shanahan gave up play-calling duties in a ...

After a challenging year leading the San Francisco 49ers, Kyle Shanahan delivered a subtle but reassuring message to fans, ...

Explore the latest NFL Draft order and first-round scenarios for every team. Stay updated on potential picks and key draft ...

Now that the NFL's regular season has ended, for most football fans, the next big event on their radar is Super Bowl 59.

The New York Jets reportedly want to interview another San Francisco 49ers assistant for their vacant head coach position.

Walter Nolen, Seth Campbell and Deontae Lawson are three prospects the 49ers need to target in the 2025 NFL Draft ...