The Pirates are 1-3 over their last four games and coming off a series loss to the Astros. However, Pittsburgh has won four of the last five with Falter pitching. The Phillies are 1-6 in the past seven games and lost the past two series ahead of the Keystone State rivalry.

Get Houston vs Pittsburgh baseball betting preview, spread and over/under insights for their matchup on June 5.

Framber Valdez threw an 83-pitch complete game in his last start and returns to the mound for the Houston Astros as they end a three-game series in Pittsburgh. Mitch Keller (1-7, 3.73) pitches for Pittsburgh.