Clinical practice guidelines for the diagnosis and treatment of progressive pulmonary fibrosis (PPF) in adults were published in 2022 through collaboration among the American Thoracic Society (ATS), ...

GCLC-mediated suppression of ferroptosis contributes to lenvatinib resistance in HCC organoids and xenografts. Functional genomic screening revealed that hepatocellular carcinoma (HCC) survival ...

An ongoing open-label extension study suggests that the therapy's benefits may extend through at least 52 weeks. Deupirfenidone (LYT-100), a next-generation antifibrotic therapy, demonstrated a ...

Rituximab was linked to nearly triple the risk of hypogammaglobulinemia in the discovery cohort and a nearly 5-fold higher risk in the larger validation cohort. Patients with multiple sclerosis (MS) ...

Intercept Pharmaceuticals, the developer of the PBC drug, suggested that the company's view on the drug's benefit and risk profile differed from that of the US Food and Drug Administration.

A comprehensive hematologic assessment can be useful in cases of CAD without common etiologies. “While CAD is most commonly linked to clonal B-cell disorders such as chronic lymphocytic leukemia and ...

In this episode of the Rare Care podcast, Larry Luxner, senior correspondent for Rare Disease Advisor, interviews Kfir Oved, PhD, about the latest Israeli research on myasthenia gravis (MG). Dr. Oved ...

Microscopic examination of the patient's fibroblasts after treatment revealed improved FXN levels. Antisense oligonucleotide (ASO) therapy appears to be a viable therapeutic alternative for Friedreich ...

Immunohistochemistry can identify concomitant SM in acute myeloid leukemia, leading to better risk stratification and management. The most common forms of AML in pediatric patients are those ...

Patients with MF and anemia treated with momelotinib made total savings of CAD$82,551 compared to those given ruxolitinib or treated with best available therapy. Momelotinib is cost-effective compared ...

Adding antioxidants such as Trolox, Resveratrosl, and MitoTempo to the cooling regimen boosted the protection, even at higher temperatures, including 26°C. Hair loss due to the rigorous chemotherapy ...

Carolina Barnett-Tapia, MD, PhD, is an associate professor of neurology at the University of Toronto. Larry Luxner, senior correspondent for Rare Disease Advisor, interviews Carolina Barnett-Tapia, MD ...